{"id":29477,"date":"2023-08-01T11:36:29","date_gmt":"2023-08-01T15:36:29","guid":{"rendered":"https:\/\/centroincar.cl\/?p=29477"},"modified":"2024-02-26T14:11:51","modified_gmt":"2024-02-26T18:11:51","slug":"investigacion-de-uach-unab-incar-y-cisa-determino-que-ipvn-induciria-cambios-en-genes-claves-del-sistema-inmunitario-de-truchas-arcoiris","status":"publish","type":"post","link":"https:\/\/centroincar.cl\/en\/2023\/08\/01\/investigacion-de-uach-unab-incar-y-cisa-determino-que-ipvn-induciria-cambios-en-genes-claves-del-sistema-inmunitario-de-truchas-arcoiris\/","title":{"rendered":"Research by UACh, UNAB, INCAR and CISA determined that IPVN would induce changes in key genes of the immune system of rainbow trout"},"content":{"rendered":"<p>A collaboration between researchers from the Universidad Austral de Chile (UACh), Universidad Andr\u00e9s Bello (UNAB), the Interdisciplinary Center for Aquaculture Research (INCAR), and the Animal Health Research Center (CISA) in Spain has determined that the Infectious Pancreatic Necrosis Virus (IPNV) is capable of altering the expression of key genes in the immune system of rainbow trout through epigenetic mechanisms. The study titled &#8220;Epigenetic reprogramming around IFN1 and IFNy2 promoters in rainbow trout cells inoculated with infectious pancreatic necrosis virus (IPNV)&#8221;, authored by Ren\u00e9 Manr\u00edquez, Mois\u00e9s Sandoval, Carlos Loncoman, Carolina Tafalla, Ruben Avenda\u00f1o-Herrera, and Juan Guillermo C\u00e1rcamo, would be the first to demonstrate the effect of epigenetic reprogramming after IPNV infection in salmonid cells. &#8220;This demonstrates that the level of promoter methylation\/demethylation and changes in histone code associated with the promoters may play a role in modulating the immune response induced by the virus,&#8221; explain the researchers.<\/p>\n<p>&nbsp;<\/p>\n<p>For more information, please <a href=\"https:\/\/doi.org\/10.1016\/j.fsi.2023.108947\" target=\"_blank\" rel=\"noopener\">read the manuscript published in \u00a0Fish &amp; Shellfish Immunology<\/a> in the following link.<\/p>","protected":false},"excerpt":{"rendered":"<p>A collaboration between researchers from the Universidad Austral de Chile (UACh), Universidad Andr\u00e9s Bello (UNAB), the Interdisciplinary Center for Aquaculture Research (INCAR), and the Animal Health Research Center (CISA) in Spain has determined that the Infectious Pancreatic Necrosis Virus (IPNV) is capable of altering the expression of key genes in the immune system of rainbow [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":29478,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-29477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias"],"acf":[],"views":1832,"_links":{"self":[{"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/posts\/29477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/comments?post=29477"}],"version-history":[{"count":1,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/posts\/29477\/revisions"}],"predecessor-version":[{"id":30440,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/posts\/29477\/revisions\/30440"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/media\/29478"}],"wp:attachment":[{"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/media?parent=29477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/categories?post=29477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/centroincar.cl\/en\/wp-json\/wp\/v2\/tags?post=29477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}