Dr. Diego Valenzuela Miranda is a prominent researcher at the INCAR Center, specializing in genomics and bioinformatics applied to aquaculture. His work focuses on studying the interaction between the environment, aquatic organisms, and their pathogens, with particular attention to salmon and aquaculture-relevant invertebrates.
His research includes studying the molecular responses of aquatic organisms to pathogens and environmental fluctuations, as well as understanding the role of microbiota in regulating these responses. Additionally, Dr. Valenzuela has collaborated on genome sequencing projects of aquaculture-relevant species and has led research projects funded by FONDECYT and FONDEF, among others.
2019 Doctor en Ciencias con mención en Manejo de Recursos Acuáticos Renovables, Universidad de Concepción, Chile
2019 Doctor en Ciencias con mención en Manejo de Recursos Acuáticos Renovables, Universidad de Concepción, Chile
Valenzuela-Muñoz, V.; Núñez-Acuña, G.; Roberts, S.; Garcia, A.; Valdés, J.A.; Valenzuela-Miranda, D.; Gallardo-Escárate, C. (2024). Environmental influence on the Atlantic salmon transcriptome and methylome during sea lice infestations. Fish and Shellfish Immunology. Vol.151.1-11
Montúfar-Romero, M.; Valenzuela-Muñoz, V.; Valenzuela-Miranda, D.; Gallardo-Escárate (2024). Hypoxia in the Blue Mussel Mytilus chilensis Induces a Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response.Genes Vol.15(6)2- 31
Valenzuela-Miranda, Diego; Valenzuela-Munoz, Valentina; Benavente, Barbara P.; Munoz-Trorcoso, Marcelo; Nunez-Acuna, Gustavo; Gallardo-Escarate, Cristian (2024). The Atlantic salmon microbiome infected with the sea louse Caligus rogercresseyi reveals tissue-specific functional dysbiosis AQUACULTURE. Vol.580. 1-11.
Nunez-Acuna, Gustavo; Saez-Vera, Constanza; Valenzuela-Miranda, Diego; Valenzuela-Munoz, Valentina; Gallardo-Escarate, Cristian. (2023). Whole-genome resequencing in the sea louse Caligus rogercresseyi uncovers gene duplications and copy number variants associated with pesticide resistance. FRONTIERS IN MARINE SCIENCE Vol.10.1-14.
Valenzuela-Munoz, Valentina; Gallardo-Escarate, Cristian; Valenzuela-Miranda, Diego; Nunez-Acuna, Gustavo; Benavente, Barbara P.; Alert, Alejandro; Arevalo, Marta. (2023). Transcriptome Signatures of Atlantic Salmon-Resistant Phenotypes against Sea Lice Infestation Are Associated with Tissue Repair. GENES Vol.14. 1-15.
Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Valenzuela-Miranda, Diego; Tapia, Fabian J.; Yevenes, Marco; Gajardo, Gonzalo; Toro, Jorge E.; Oyarzun, Pablo A.; Arriagada, Gloria; Novoa, Beatriz; Figueras, Antonio; Roberts, Steven; Gerdol, Marco (2023). Chromosome-Level Genome Assembly of the Blue Mussel Mytilus chilensis Reveals Molecular Signatures Facing the Marine Environmen GENES. Vol.14. 1-27.
Morales-Rivera, Maria F.; Valenzuela-Miranda, Diego; Nunez-Acuna, Gustavo; Benavente, Barbara P.; Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina. (2023). Atlantic Salmon (Salmo salar) Transfer to Seawater by Gradual Salinity Changes Exhibited an Increase in The Intestinal Microbial Abundance and Richness MICROORGANISMS. Vol. 11. 1-15.
Gallardo-Escárate, C.; Valenzuela-Muñoz, V.; Nuñez-Acuña, G.; Valenzuela-Miranda, D. ; Tapia, F.; Yevenes, M.; Gajardo, G.; Toro, J.E.; Oyarzun, P.A.; Arriagada, G.; Novoa, B.; Figueras, A.; Roberts, S.; Gerdol, M. (2022). The native mussel Mytilus chilensis genoma reveals adaptive molecular signatures facing the marine environment. Molecular Ecology. Vol. 0. 1-39.
Casuso, Antonio; Valenzuela-Munoz, Valentina; Benavente, Barbara P.; Valenzuela-Miranda, Diego; Gallardo-Escarate, Cristian (2022). Exploring Sea Lice Vaccines against Early Stages of Infestation in Atlantic Salmon (Salmo salar). VACCINES. Vol. 10.1-23.
Morales-Rivera, María F.; Valenzuela-Miranda, Diego; Valenzuela-Muñoz, Valentina; Nuñez-Acuña, Gustavo; Avendaño-Herrera, Ruben; Gallardo-Escárate, Cristian (2022). Nanopore sequencing evidenced the presence of fish bacterial pathogens in the sea louse (Caligus rogercresseyi) microbiota collected from distant salmon farms in Chile. Aquaculture. Vol. 552. 738026-738033.
Valenzuela-Muñoz, Valentina; Gallardo-Escárate, Cristian; Benavente, Bárbara P.; Valenzuela-Miranda, Diego; Núñez-Acuña, Gustavo; Escobar-Sepulveda, Hugo; Váldes, Juan Antonio. (2022). Whole-Genome Transcript Expression Profiling Reveals Novel Insights into Transposon Genes and Non-Coding RNAs during Atlantic Salmon Seawater Adaptation Biology. Vol. 11. 1-21.
Valenzuela-Munoz, Valentina; Benavente, Barbara P.; Casuso, Antonio; Leal, Yeny; Valenzuela-Miranda, Diego; Nunez-Acuna, Gustavo; Saez-Vera, Constanza; Gallardo-Escarate, Cristian (2021). Transcriptome and morphological analysis in Caligus rogercresseyi uncover the effects of Atlantic salmon vaccination with IPath (R) FISH SHELLFISH IMMUNOLOGY. Vol. 117. 169-178.
Nunez-Acuna, Gustavo; Valenzuela-Munoz, Valentina; Valenzuela-Miranda, Diego; Gallardo-Escarate, Cristian (2021). Comprehensive Transcriptome Analyses in Sea Louse Reveal Novel Delousing Drug Responses Through MicroRNA regulation MARINE BIOTECHNOLOGY. Vol. 23. 710-723.
Núñez-Acuña, Gustavo; Valenzuela-Muñoz, Valentina; Carrera-Naipil, Crisleri; Sáez-Vera, Constanza; Benavente, Bárbara P.; Valenzuela-Miranda, Diego; Gallardo-Escárate, Cristian (2021). Trypsin Genes Are Regulated through the miRNA Bantam and Associated with Drug Sensitivity in the Sea Louse Caligus rogercresseyi Non-Coding RNA. Vol. 7.76-93.
Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Valenzuela-Miranda, Diego; Benaventel, Barbara P.; Saez-Vera, Constanza; Urrutia, Homero; Novoa, Beatriz; Figueras, Antonio; Roberts, Steven; Assmann, Paulina; Bravo, Marta. (2021). The wastewater microbiome: A novel insight for COVID-19 surveillance SCIENCE OF THE TOTAL ENVIRONMENT. Vol. 764.142867-142877.
Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Valenzuela-Miranda, Diego; Goncalves, Ana Teresa; Escobar-Sepulveda, Hugo; Liachko, Ivan; Nelson, Bradley; Roberts, Steven; Warren, Wesley. (2021). Chromosome-scale genome assembly of the sea louse Caligus rogercresseyi by SMRT sequencing and Hi-C analysis SCIENTIFIC DATA. Vol. 8. 1-12.