Three INCAR researchers’ projects will be funded by FONDECYT:
“Assessment of heterologous effects of vaccines used in the salmon industry: immunogenomics for the generation of post-vaccination health biomarkers.”
Dr. Antonio Casuso, researcher from the Aquaculture Genomics line, was awarded a Postdoctoral Fondecyt grant. The objective of this project is to determine a vaccination window that ensures greater protection in Atlantic salmon by evaluating transcriptional and epigenetic patterns in fish immunized with commercial vaccines.
“Protein identification and mechanisms associated with drug resistance in the salmon parasite Caligus rogercresseyi.”
Dr. Juan Guillermo Cárcamo, academic from the Austral University of Chile (UACh) and Associate Researcher at INCAR, won a Regular Fondecyt grant. The objective of this project is to functionally identify proteins and molecular mechanisms associated with drug resistance in the salmon parasite Caligus rogercresseyi, contrasting specimens that are sensitive and resistant to different antiparasitic treatments.
“A study on how the bacteria Renibacterium salmoninarum survives within cells and evades the immune system of Atlantic salmon, disrupting cellular death processes, through laboratory and fish-based testing.”
Dr. Alejandro Yáñez, academic at Universidad Austral de Chile, was awarded a Regular Fondecyt grant. The project involves the collaboration of Adolfo Isla, researcher from the “Marine Animal Health” line at INCAR. I this project, the researchers will analyze the genome of Atlantic salmon in silico to determine homologous PANoptosis genes and compare them with genes from mammals and bony fish. The goal is to determine if Renibacterium salmoninarum inhibits the activation of cellular PANoptosis as a mechanism for intracellular survival and evasion of the immune response in Atlantic salmon.
